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Directed evolution of an α1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method

Fucosylated glycoconjugates are involved in a variety of physiological and pathological processes. However, economical production of fucosylated drugs and prebiotic supplements has been hampered by the poor catalytic efficiency of fucosyltransferases. Here, we developed a fluorescence-activated cell...

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Detalles Bibliográficos
Autores principales:	Tan, Yumeng, Zhang, Yong, Han, Yunbin, Liu, Hao, Chen, Haifeng, Ma, Fuqiang, Withers, Stephen G., Feng, Yan, Yang, Guangyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785251/ https://www.ncbi.nlm.nih.gov/pubmed/31633018 http://dx.doi.org/10.1126/sciadv.aaw8451

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