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Habenular and striatal activity during performance feedback are differentially linked with state-like and trait-like aspects of tobacco use disorder

The habenula, an epithalamic nucleus involved in reward and aversive processing, may contribute to negative reinforcement mechanisms maintaining nicotine use. We used a performance feedback task that differentially activates the striatum and habenula and administered nicotine and varenicline (versus...

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Detalles Bibliográficos
Autores principales: Flannery, Jessica S., Riedel, Michael C., Poudel, Ranjita, Laird, Angela R., Ross, Thomas J., Salmeron, Betty Jo, Stein, Elliot A., Sutherland, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785263/
https://www.ncbi.nlm.nih.gov/pubmed/31633021
http://dx.doi.org/10.1126/sciadv.aax2084