Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving

Neuroadaptations in the nucleus accumbens (NAc) underlie cue-induced cocaine craving that intensifies (“incubates”) during abstinence and is believed to contribute to persistent relapse vulnerability. Changes in gene expression often govern perpetual behavioral abnormalities, but epigenetic plastici...

Descripción completa

Detalles Bibliográficos
Autores principales: Werner, C. T., Mitra, S., Martin, J. A., Stewart, A. F., Lepack, A. E., Ramakrishnan, A., Gobira, P. H., Wang, Z.-J., Neve, R. L., Gancarz, A. M., Shen, L., Maze, I., Dietz, D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785264/
https://www.ncbi.nlm.nih.gov/pubmed/31633032
http://dx.doi.org/10.1126/sciadv.aay0351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785264/
https://www.ncbi.nlm.nih.gov/pubmed/31633032
http://dx.doi.org/10.1126/sciadv.aay0351

Ejemplares similares