Pten loss results in inappropriate excitatory connectivity

Pten mutations are associated with Autism Spectrum Disorder. Pten loss of function in neurons increases excitatory synaptic connectivity, contributing to an imbalance between excitation and inhibition. We aimed to determine whether Pten loss results in aberrant connectivity in neural circuits. We co...

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Detalles Bibliográficos
Autores principales: Skelton, Patrick D., Frazel, Paul W., Lee, Daehoon, Suh, Hoonkyo, Luikart, Bryan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785382/
https://www.ncbi.nlm.nih.gov/pubmed/30967683
http://dx.doi.org/10.1038/s41380-019-0412-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785382/
https://www.ncbi.nlm.nih.gov/pubmed/30967683
http://dx.doi.org/10.1038/s41380-019-0412-6

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