Cargando…
Genome‐wide meta‐analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans
BACKGROUND: Left ventricular (LV) hypertrophy affects up to 43% of African Americans (AAs). Antihypertensive treatment reduces LV mass (LVM). However, interindividual variation in LV traits in response to antihypertensive treatments exists. We hypothesized that genetic variants may modify the associ...
Autores principales: | Do, Anh N., Zhao, Wei, Baldridge, Abigail S., Raffield, Laura M., Wiggins, Kerri L., Shah, Sanjiv J., Aslibekyan, Stella, Tiwari, Hemant K., Limdi, Nita, Zhi, Degui, Sitlani, Colleen M., Taylor, Kent D., Psaty, Bruce M., Sotoodehnia, Nona, Brody, Jennifer A., Rasmussen‐Torvik, Laura J., Lloyd‐Jones, Donald, Lange, Leslie A., Wilson, James G., Smith, Jennifer A., Kardia, Sharon L. R., Mosley, Thomas H., Vasan, Ramachandran S., Arnett, Donna K., Irvin, Marguerite R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785453/ https://www.ncbi.nlm.nih.gov/pubmed/31407531 http://dx.doi.org/10.1002/mgg3.788 |
Ejemplares similares
-
The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study
por: Do, Anh N., et al.
Publicado: (2014) -
Local Ancestry and Clinical Cardiovascular Events Among African Americans From the Atherosclerosis Risk in Communities Study
por: Shendre, Aditi, et al.
Publicado: (2017) -
Genome-wide meta-analysis of SNP-by-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry
por: Irvin, Marguerite R, et al.
Publicado: (2018) -
Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium
por: Bis, Joshua C., et al.
Publicado: (2015) -
Plasma sphingolipids, lung function and COPD: the Cardiovascular Health Study
por: Gharib, Arya R., et al.
Publicado: (2023)