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Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer

BACKGROUND: Pancreatic cancer is a major cause of cancer-related death, with a 5-year overall survival rate being below 5%. The main causes of poor prognosis in pancreatic cancer include easy metastasis, high recurrence rate, and robust drug resistance. Gemcitabine is a first-line drug for patients...

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Detalles Bibliográficos
Autores principales: Wei, Li, Wen, Jing-Yun, Chen, Jie, Ma, Xiao-Kun, Wu, Dong-Hao, Chen, Zhan-Hong, Huang, Jiang-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785518/
https://www.ncbi.nlm.nih.gov/pubmed/31602160
http://dx.doi.org/10.3748/wjg.v25.i37.5590