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Crosstalk between protein N-glycosylation and lipid metabolism in Saccharomyces cerevisiae

The endoplasmic reticulum (ER) is a multi functional organelle and plays a crucial role in protein folding and lipid biosynthesis. The SEC59 gene encodes dolichol kinase, required for protein glycosylation in the ER. The mutation of sec59-1 caused a protein N-glycosylation defect mediated ER stress...

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Detalles Bibliográficos
Autores principales: William James, Antonisamy, Ravi, Chidambaram, Srinivasan, Malathi, Nachiappan, Vasanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785544/
https://www.ncbi.nlm.nih.gov/pubmed/31597940
http://dx.doi.org/10.1038/s41598-019-51054-7