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Crosstalk between protein N-glycosylation and lipid metabolism in Saccharomyces cerevisiae
The endoplasmic reticulum (ER) is a multi functional organelle and plays a crucial role in protein folding and lipid biosynthesis. The SEC59 gene encodes dolichol kinase, required for protein glycosylation in the ER. The mutation of sec59-1 caused a protein N-glycosylation defect mediated ER stress...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785544/ https://www.ncbi.nlm.nih.gov/pubmed/31597940 http://dx.doi.org/10.1038/s41598-019-51054-7 |