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The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia
A recent development in the genetic architecture of schizophrenia suggested that an omnigenic model may underlie the risk for this disorder. The aim of our study was to use polygenic profile scoring to quantitatively assess whether a number of experimentally derived sets would contribute to the diso...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785707/ https://www.ncbi.nlm.nih.gov/pubmed/31078131 http://dx.doi.org/10.1038/s41386-019-0410-z |