Cargando…

The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia

A recent development in the genetic architecture of schizophrenia suggested that an omnigenic model may underlie the risk for this disorder. The aim of our study was to use polygenic profile scoring to quantitatively assess whether a number of experimentally derived sets would contribute to the diso...

Descripción completa

Detalles Bibliográficos
Autores principales: Rammos, Alexandros, Gonzalez, Lara A. Neira, Weinberger, Daniel R., Mitchell, Kevin J., Nicodemus, Kristin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785707/
https://www.ncbi.nlm.nih.gov/pubmed/31078131
http://dx.doi.org/10.1038/s41386-019-0410-z