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Synergistic induction of apoptosis in a cell model of human leukemia K562 by nitroglycerine and valproic acid

Nitroglycerin (NG), a nitric oxide donor, and valproic acid (VPA), an inhibitor of histone deacetylases, have impressive effects on numerous cancer cell lines. This study intended to evaluate synergistic effects of NG and VPA on cell viability and apoptosis in K562 cells. K562 cells were cultured in...

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Detalles Bibliográficos
Autores principales: Aalaei, Shahin, Mohammadzadeh, Mehdi, Pazhang, Yaghub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785758/
https://www.ncbi.nlm.nih.gov/pubmed/31611745
http://dx.doi.org/10.17179/excli2019-1581