Up-regulation of miR-381 inhibits NAD+ salvage pathway and promotes apoptosis in breast cancer cells

Nicotinamide phosphoribosyltransferase (NAMPT), a rate-limiting enzyme involved in nicotinamide adenine dinucleotide (NAD) salvage pathway, is overexpressed in many human malignancies such as breast cancer. This enzyme plays a critical role in survival and growth of cancer cells. MicroRNAs (miRNAs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Bolandghamat Pour, Zahra, Nourbakhsh, Mitra, Mousavizadeh, Kazem, Madjd, Zahra, Ghorbanhosseini, Seyedeh Sara, Abdolvahabi, Zohreh, Hesari, Zahra, Mobaser, Samira Ezzati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785761/
https://www.ncbi.nlm.nih.gov/pubmed/31611752
http://dx.doi.org/10.17179/excli2019-1431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785761/
https://www.ncbi.nlm.nih.gov/pubmed/31611752
http://dx.doi.org/10.17179/excli2019-1431

Ejemplares similares