Cargando…

Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in rats

BACKGROUND: Laminectomy is usually classed as a common orthopedic surgery, but postoperative epidural fibrosis often leads to less-than-desirable clinical outcomes. As demonstrated by prior studies, emodin (EMO) exerts an anti-fibrotic effect. Here, we carried out investigation into the inhibitory e...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Guirun, Chen, Hui, Wan, Qi, Dai, Jihang, Sun, Yu, Wang, Jingcheng, Li, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785852/
https://www.ncbi.nlm.nih.gov/pubmed/31601256
http://dx.doi.org/10.1186/s13018-019-1357-9