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Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in rats
BACKGROUND: Laminectomy is usually classed as a common orthopedic surgery, but postoperative epidural fibrosis often leads to less-than-desirable clinical outcomes. As demonstrated by prior studies, emodin (EMO) exerts an anti-fibrotic effect. Here, we carried out investigation into the inhibitory e...
Autores principales: | Xiong, Guirun, Chen, Hui, Wan, Qi, Dai, Jihang, Sun, Yu, Wang, Jingcheng, Li, Xiaolei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785852/ https://www.ncbi.nlm.nih.gov/pubmed/31601256 http://dx.doi.org/10.1186/s13018-019-1357-9 |
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