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Relating the gut metagenome and metatranscriptome to immunotherapy responses in melanoma patients

BACKGROUND: Recent evidence suggests that immunotherapy efficacy in melanoma is modulated by gut microbiota. Few studies have examined this phenomenon in humans, and none have incorporated metatranscriptomics, important for determining expression of metagenomic functions in the microbial community....

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Detalles Bibliográficos
Autores principales: Peters, Brandilyn A., Wilson, Melissa, Moran, Una, Pavlick, Anna, Izsak, Allison, Wechter, Todd, Weber, Jeffrey S., Osman, Iman, Ahn, Jiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785875/
https://www.ncbi.nlm.nih.gov/pubmed/31597568
http://dx.doi.org/10.1186/s13073-019-0672-4