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Nanoaperture fabrication via colloidal lithography for single molecule fluorescence analysis

In single molecule fluorescence studies, background emission from labeled substrates often restricts their concentrations to non-physiological nanomolar values. One approach to address this challenge is the use of zero-mode waveguides (ZMWs), nanoscale holes in a thin metal film that physically and...

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Detalles Bibliográficos
Autores principales: Jamiolkowski, Ryan M., Chen, Kevin Y., Fiorenza, Shane A., Tate, Alyssa M., Pfeil, Shawn H., Goldman, Yale E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786550/
https://www.ncbi.nlm.nih.gov/pubmed/31600217
http://dx.doi.org/10.1371/journal.pone.0222964