Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner

Many in vivo studies suggest that inhalational anesthetics can accelerate or prevent the progression of neuropathology and cognitive impairments in Alzheimer Disease (AD), but the synaptic mechanisms mediating these ambiguous effects are unclear. Here, we show that repeated exposures of neonatal and...

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Detalles Bibliográficos
Autores principales: Joseph, Donald J., Liu, Chunxia, Peng, Jun, Liang, Ge, Wei, Huafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786564/
https://www.ncbi.nlm.nih.gov/pubmed/31600350
http://dx.doi.org/10.1371/journal.pone.0223509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786564/
https://www.ncbi.nlm.nih.gov/pubmed/31600350
http://dx.doi.org/10.1371/journal.pone.0223509

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