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Plasma mitochondrial DNA is elevated in obese type 2 diabetes mellitus patients and correlates positively with insulin resistance

Cells damaged by mechanical or infectious injury release proinflammatory mitochondrial DNA (mtDNA) fragments into the circulation. We evaluated the relation between plasma levels of mtDNA fragments in obese type 2 diabetes mellitus (T2DM) patients and measures of chronic inflammation and insulin res...

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Detalles Bibliográficos
Autores principales: Yuzefovych, Larysa V., Pastukh, Viktor M., Ruchko, Mykhaylo V., Simmons, Jon D., Richards, William O., Rachek, Lyudmila I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786592/
https://www.ncbi.nlm.nih.gov/pubmed/31600210
http://dx.doi.org/10.1371/journal.pone.0222278