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Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis

The interplay between signalling pathways and metabolism is crucial for tissue growth. Yet, it remains poorly understood. Here, we studied the consequences of modulating iron metabolism on the growth of Drosophila imaginal discs. We find that reducing the levels of the ferritin heavy chain in the la...

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Detalles Bibliográficos
Autores principales: Mumbauer, Simone, Pascual, Justine, Kolotuev, Irina, Hamaratoglu, Fisun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786644/
https://www.ncbi.nlm.nih.gov/pubmed/31568497
http://dx.doi.org/10.1371/journal.pgen.1008396