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N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

The functions of FGF receptors (FGFRs) in early development of the cerebral cortex are well established. Their functions in the migration of neocortical projection neurons, however, are unclear. We have found that FGFRs regulate multipolar neuron orientation and the morphological change into bipolar...

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Detalles Bibliográficos
Autores principales: Kon, Elif, Calvo-Jiménez, Elisa, Cossard, Alexia, Na, Youn, Cooper, Jonathan A, Jossin, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786859/
https://www.ncbi.nlm.nih.gov/pubmed/31577229
http://dx.doi.org/10.7554/eLife.47673