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Asparagine Deprivation Causes a Reversible Inhibition of Human Cytomegalovirus Acute Virus Replication

As obligate intracellular pathogens, viruses rely on the host cell machinery to replicate efficiently, with the host metabolism extensively manipulated for this purpose. High-throughput small interfering RNA (siRNA) screens provide a systematic approach for the identification of novel host-virus int...

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Detalles Bibliográficos
Autores principales: Lee, Chen-Hsuin, Griffiths, Samantha, Digard, Paul, Pham, Nhan, Auer, Manfred, Haas, Juergen, Grey, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786868/
https://www.ncbi.nlm.nih.gov/pubmed/31594813
http://dx.doi.org/10.1128/mBio.01651-19