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Differential Clinical Significance of Neurotrophin-3 Expression according to MYCN Amplification and TrkC Expression in Neuroblastoma

BACKGROUND: Neurotrophin-3 (NT-3), a member of the NT family, has only been considered an ancillary compound that provides anti-apoptotic benefits by inactivating tropomyosin receptor kinase C (TrkC)-induced apoptotic signals. However, little is known about the clinical relevance of NT-3 expression...

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Detalles Bibliográficos
Autores principales: Seo, Eunseop, Kim, Jung-Sun, Ma, Young Eun, Cho, Hee Won, Ju, Hee Young, Lee, Soo Hyun, Lee, Ji Won, Yoo, Keon Hee, Sung, Ki Woong, Koo, Hong Hoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786962/
https://www.ncbi.nlm.nih.gov/pubmed/31602824
http://dx.doi.org/10.3346/jkms.2019.34.e254