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A novel 3D nanofibre scaffold conserves the plasticity of glioblastoma stem cell invasion by regulating galectin-3 and integrin-β1 expression

Glioblastoma Multiforme (GBM) invasiveness renders complete surgical resection impossible and highly invasive Glioblastoma Initiating Cells (GICs) are responsible for tumour recurrence. Their dissemination occurs along pre-existing fibrillary brain structures comprising the aligned myelinated fibres...

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Detalles Bibliográficos
Autores principales: Saleh, Ali, Marhuenda, Emilie, Fabre, Christine, Hassani, Zahra, Weille, Jan de, Boukhaddaoui, Hassan, Guelfi, Sophie, Maldonado, Igor Lima, Hugnot, Jean- Philippe, Duffau, Hugues, Bauchet, Luc, Cornu, David, Bakalara, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787018/
https://www.ncbi.nlm.nih.gov/pubmed/31601895
http://dx.doi.org/10.1038/s41598-019-51108-w