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A novel 3D nanofibre scaffold conserves the plasticity of glioblastoma stem cell invasion by regulating galectin-3 and integrin-β1 expression
Glioblastoma Multiforme (GBM) invasiveness renders complete surgical resection impossible and highly invasive Glioblastoma Initiating Cells (GICs) are responsible for tumour recurrence. Their dissemination occurs along pre-existing fibrillary brain structures comprising the aligned myelinated fibres...
Autores principales: | Saleh, Ali, Marhuenda, Emilie, Fabre, Christine, Hassani, Zahra, Weille, Jan de, Boukhaddaoui, Hassan, Guelfi, Sophie, Maldonado, Igor Lima, Hugnot, Jean- Philippe, Duffau, Hugues, Bauchet, Luc, Cornu, David, Bakalara, Norbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787018/ https://www.ncbi.nlm.nih.gov/pubmed/31601895 http://dx.doi.org/10.1038/s41598-019-51108-w |
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