Cargando…
Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets
Lipid availability within transmembrane nano-pockets of ion channels is linked with mechanosensation. However, the effect of hindering lipid-chain penetration into nano-pockets on channel structure has not been demonstrated. Here we identify nano-pockets on the large conductance mechanosensitive cha...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787021/ https://www.ncbi.nlm.nih.gov/pubmed/31601809 http://dx.doi.org/10.1038/s41467-019-12591-x |