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MiR-499 Responsive Lethal Construct for Removal of Human Embryonic Stem Cells after Cardiac Differentiation

Deriving cell populations from human embryonic stem cells (hESCs) for cell-based therapy is considered a promising strategy to achieve functional cells, yet its translation to clinical practice depends on achieving fully defined differentiated cells. In this work, we generated a miRNA-responsive let...

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Detalles Bibliográficos
Autores principales: Elovic, Edan, Etzion, Sharon, Cohen, Smadar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787023/
https://www.ncbi.nlm.nih.gov/pubmed/31601830
http://dx.doi.org/10.1038/s41598-019-50899-2