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N(6)-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

Many of the regulatory features governing erythrocyte specification, maturation, and associated disorders remain enigmatic. To identify new regulators of erythropoiesis, we utilize a functional genomic screen for genes affecting expression of the erythroid marker CD235a/GYPA. Among validating hits a...

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Detalles Bibliográficos
Autores principales: Kuppers, Daniel A., Arora, Sonali, Lim, Yiting, Lim, Andrea R., Carter, Lucas M., Corrin, Philip D., Plaisier, Christopher L., Basom, Ryan, Delrow, Jeffrey J., Wang, Shiyan, Hansen He, Housheng, Torok-Storb, Beverly, Hsieh, Andrew C., Paddison, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787028/
https://www.ncbi.nlm.nih.gov/pubmed/31601799
http://dx.doi.org/10.1038/s41467-019-12518-6