Induced pluripotent stem cells-derived neurons from patients with Friedreich ataxia exhibit differential sensitivity to resveratrol and nicotinamide

Translation of pharmacological results from in vitro cell testing to clinical trials is challenging. One of the causes that may underlie these discrepant results is the lack of the phenotypic or species-specific relevance of the tested cells; today, this lack of relevance may be reduced by relying o...

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Detalles Bibliográficos
Autores principales: Georges, Pauline, Boza-Moran, Maria-Gabriela, Gide, Jacqueline, Pêche, Georges Arielle, Forêt, Benjamin, Bayot, Aurélien, Rustin, Pierre, Peschanski, Marc, Martinat, Cécile, Aubry, Laetitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787055/
https://www.ncbi.nlm.nih.gov/pubmed/31601825
http://dx.doi.org/10.1038/s41598-019-49870-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787055/
https://www.ncbi.nlm.nih.gov/pubmed/31601825
http://dx.doi.org/10.1038/s41598-019-49870-y

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