Ubiquitin receptors are required for substrate-mediated activation of the proteasome’s unfolding ability

The ubiquitin-proteasome system (UPS) is responsible for the bulk of protein degradation in eukaryotic cells, but the factors that cause different substrates to be unfolded and degraded to different extents are still poorly understood. We previously showed that polyubiquitinated substrates were degr...

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Detalles Bibliográficos
Autores principales: Cundiff, Mary D., Hurley, Christina M., Wong, Jeremy D., Boscia, Joseph A., Bashyal, Aarti, Rosenberg, Jake, Reichard, Eden L., Nassif, Nicholas D., Brodbelt, Jennifer S., Kraut, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787058/
https://www.ncbi.nlm.nih.gov/pubmed/31601863
http://dx.doi.org/10.1038/s41598-019-50857-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787058/
https://www.ncbi.nlm.nih.gov/pubmed/31601863
http://dx.doi.org/10.1038/s41598-019-50857-y

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