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Topically Applied Cross-Linked Hyaluronan Attenuates the Formation of Spinal Epidural Fibrosis in a Swine Model of Laminectomy

Epidural fibrosis is an inevitable aspect of the postoperative healing process which is one of the causes of failed back surgery syndrome following spinal surgery. The aim of the present study was to examine the inhibitory effect of 1,4-butanediol diglycidyl ether-crosslinked hyaluronan (cHA) on spi...

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Detalles Bibliográficos
Autores principales: Lin, Cheng-Li, Jou, I-Ming, Wu, Cheng-Yi, Kuo, Yuh-Ruey, Yang, Shih-Chieh, Lee, Jung-Shun, Tu, Yuan-Kun, Chen, Sung-Ching, Huang, Yi-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787060/
https://www.ncbi.nlm.nih.gov/pubmed/31601849
http://dx.doi.org/10.1038/s41598-019-50882-x