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Esters of terpene alcohols as highly potent, reversible, and low toxic skin penetration enhancers

Skin penetration/permeation enhancers are compounds that improve (trans)dermal drug delivery. We designed hybrid terpene-amino acid enhancers by conjugating natural terpenes (citronellol, geraniol, nerol, farnesol, linalool, perillyl alcohol, menthol, borneol, carveol) or cinnamyl alcohol with 6-(di...

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Detalles Bibliográficos
Autores principales: Kopečná, Monika, Macháček, Miloslav, Nováčková, Anna, Paraskevopoulos, Georgios, Roh, Jaroslav, Vávrová, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787078/
https://www.ncbi.nlm.nih.gov/pubmed/31601936
http://dx.doi.org/10.1038/s41598-019-51226-5