Retinoic Acid Receptor-Related Receptor Alpha Ameliorates Autoimmune Arthritis via Inhibiting of Th17 Cells and Osteoclastogenesis

Rheumatoid arthritis (RA) is a chronic inflammatory polyarthritis characterized by progressive joint destruction. IL-17-producing CD4(+) T (Th17) cells play pivotal roles in RA development and progression. Retinoic acid receptor-related orphan receptor alpha (RORα) is a negative regulator of inflamm...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Jin-Sil, Moon, Su-Jin, Lim, Mi-Ae, Byun, Jae-Kyeong, Hwang, Sun-Hee, Yang, SeungCheon, Kim, Eun-Kyung, Lee, Hohyun, Kim, Sung-Min, Lee, Jennifer, Kwok, Seung-Ki, Min, Jun-Ki, Lee, Mi-Ock, Shin, Dong-Yun, Park, Sung-Hwan, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787168/
https://www.ncbi.nlm.nih.gov/pubmed/31636631
http://dx.doi.org/10.3389/fimmu.2019.02270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787168/
https://www.ncbi.nlm.nih.gov/pubmed/31636631
http://dx.doi.org/10.3389/fimmu.2019.02270

Ejemplares similares