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Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy

The retention using selective hooks (RUSH) system allows to retain a target protein fused to green fluorescent protein (GFP) and a streptavidin-binding peptide (SBP) due to the interaction with a molar excess of streptavidin molecules (“hooks”) targeted to selected subcellular compartments. Suppleme...

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Detalles Bibliográficos
Autores principales: Loos, Friedemann, Xie, Wei, Sica, Valentina, Bravo-San Pedro, José Manuel, Souquère, Sylvie, Pierron, Gérard, Lachkar, Sylvie, Sauvat, Allan, Petrazzuolo, Adriana, Jimenez, Ana Joaquina, Perez, Franck, Maiuri, Maria Chiara, Kepp, Oliver, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787181/
https://www.ncbi.nlm.nih.gov/pubmed/31601788
http://dx.doi.org/10.1038/s41419-019-2011-5