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Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions

Hepatocytes have been successfully generated from human pluripotent stem cells (hPSCs). However, the cost-effective and clinical-grade generation of hepatocytes from hPSCs still need to be improved. In this study, we reported the production of functional hepatocytes from clinical-grade human embryon...

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Detalles Bibliográficos
Autores principales: Li, Zhongwen, Wu, Jun, Wang, Lei, Han, Weifang, Yu, Juan, Liu, Xin, Wang, Yukai, Zhang, Ying, Feng, Guihai, Li, Wei, Stacey, Glyn Nigel, Gu, Qi, Hu, Baoyang, Wang, Liu, Zhou, Qi, Hao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787193/
https://www.ncbi.nlm.nih.gov/pubmed/31601782
http://dx.doi.org/10.1038/s41419-019-1967-5