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NSAIDs disrupt intestinal homeostasis by suppressing macroautophagy in intestinal epithelial cells

Small intestinal damage induced by nonsteroidal anti-inflammatory drugs (NSAIDs) remains an under-recognized clinical disorder. The incomplete understanding of the pathophysiology has hampered the development of prevention and treatment strategies leading to the high morbidity and mortality rates. N...

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Detalles Bibliográficos
Autores principales: Chamoun-Emanuelli, Ana M., Bryan, Laura K., Cohen, Noah D., Tetrault, Taylor L., Szule, Joseph A., Barhoumi, Rola, Whitfield-Cargile, Canaan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787209/
https://www.ncbi.nlm.nih.gov/pubmed/31601922
http://dx.doi.org/10.1038/s41598-019-51067-2