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BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration

Autophagy is a central component of integrated stress responses that influences many inflammatory diseases, including inflammatory bowel disease (IBD) and colorectal cancer (CRC). While the core machinery is known, the molecular basis of the epigenetic regulation of autophagy and its role in colon i...

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Detalles Bibliográficos
Autores principales: Liu, Min, Sun, Tongyu, Li, Ni, Peng, Junjie, Fu, Da, Li, Wei, Li, Li, Gao, Wei-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787222/
https://www.ncbi.nlm.nih.gov/pubmed/31601814
http://dx.doi.org/10.1038/s41467-019-12573-z