Crystal structure of ErmE - 23S rRNA methyltransferase in macrolide resistance

Pathogens often receive antibiotic resistance genes through horizontal gene transfer from bacteria that produce natural antibiotics. ErmE is a methyltransferase (MTase) from Saccharopolyspora erythraea that dimethylates A2058 in 23S rRNA using S-adenosyl methionine (SAM) as methyl donor, protecting...

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Detalles Bibliográficos
Autores principales: Stsiapanava, Alena, Selmer, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787224/
https://www.ncbi.nlm.nih.gov/pubmed/31601908
http://dx.doi.org/10.1038/s41598-019-51174-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787224/
https://www.ncbi.nlm.nih.gov/pubmed/31601908
http://dx.doi.org/10.1038/s41598-019-51174-0

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