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TCRpMHCmodels: Structural modelling of TCR-pMHC class I complexes

The interaction between the class I major histocompatibility complex (MHC), the peptide presented by the MHC and the T-cell receptor (TCR) is a key determinant of the cellular immune response. Here, we present TCRpMHCmodels, a method for accurate structural modelling of the TCR-peptide-MHC (TCR-pMHC...

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Detalles Bibliográficos
Autores principales: Jensen, Kamilla Kjærgaard, Rantos, Vasileios, Jappe, Emma Christine, Olsen, Tobias Hegelund, Jespersen, Martin Closter, Jurtz, Vanessa, Jessen, Leon Eyrich, Lanzarotti, Esteban, Mahajan, Swapnil, Peters, Bjoern, Nielsen, Morten, Marcatili, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787230/
https://www.ncbi.nlm.nih.gov/pubmed/31601838
http://dx.doi.org/10.1038/s41598-019-50932-4