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Identification and Visualization of Functionally Important Domains and Residues in Herpes Simplex Virus Glycoprotein K(gK) Using a Combination of Phylogenetics and Protein Modeling

Alphaherpesviruses are a subfamily of herpesviruses that include the significant human pathogens herpes simplex viruses (HSV) and varicella zoster virus (VZV). Glycoprotein K (gK), conserved in all alphaherpesviruses, is a multi-membrane spanning virion glycoprotein essential for virus entry into ne...

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Detalles Bibliográficos
Autores principales: Rider, Paul J. F., Coghill, Lyndon M., Naderi, Misagh, Brown, Jeremy M., Brylinski, Michal, Kousoulas, Konstantin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787236/
https://www.ncbi.nlm.nih.gov/pubmed/31601827
http://dx.doi.org/10.1038/s41598-019-50490-9