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Inhibition of dicer activity in lepidopteran and dipteran cells by baculovirus-mediated expression of Flock House virus B2

Prior studies have suggested that insect DNA viruses are negatively affected by dicer-2-mediated RNA interference (RNAi). To examine this further, we utilized an in vitro assay to measure dicer activity in lepidopteran and dipteran cells, combined with baculoviruses expressing the RNAi suppressor B2...

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Detalles Bibliográficos
Autores principales: Hodgson, Jeffrey J., Wenger, Luke W., Clem, Rollie J., Passarelli, A. Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787241/
https://www.ncbi.nlm.nih.gov/pubmed/31601846
http://dx.doi.org/10.1038/s41598-019-50851-4