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Dysregulated liver lipid metabolism and innate immunity associated with hepatic steatosis in neonatal BBdp rats and NOD mice

In a previous study we reported that prediabetic rats have a unique gene signature that was apparent even in neonates. Several of the changes we observed, including enhanced expression of pro-inflammatory genes and dysregulated UPR and metabolism genes were first observed in the liver followed by th...

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Detalles Bibliográficos
Autores principales: Serrano, D., Crookshank, J. A., Morgan, B. S., Mueller, R. W., Paré, M.-F., Marandi, L., Poussier, P., Scott, F. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787248/
https://www.ncbi.nlm.nih.gov/pubmed/31601915
http://dx.doi.org/10.1038/s41598-019-51143-7