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Dysregulated liver lipid metabolism and innate immunity associated with hepatic steatosis in neonatal BBdp rats and NOD mice
In a previous study we reported that prediabetic rats have a unique gene signature that was apparent even in neonates. Several of the changes we observed, including enhanced expression of pro-inflammatory genes and dysregulated UPR and metabolism genes were first observed in the liver followed by th...
Autores principales: | Serrano, D., Crookshank, J. A., Morgan, B. S., Mueller, R. W., Paré, M.-F., Marandi, L., Poussier, P., Scott, F. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787248/ https://www.ncbi.nlm.nih.gov/pubmed/31601915 http://dx.doi.org/10.1038/s41598-019-51143-7 |
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