Oligomeric state of the ZIKV E protein defines protective immune responses

The current leading Zika vaccine candidates in clinical testing are based on live or killed virus platforms, which have safety issues, especially in pregnant women. Zika subunit vaccines, however, have shown poor performance in preclinical studies, most likely because the antigens tested do not disp...

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Detalles Bibliográficos
Autores principales: Metz, Stefan W., Thomas, Ashlie, Brackbill, Alex, Forsberg, John, Miley, Michael J., Lopez, Cesar A., Lazear, Helen M., Tian, Shaomin, de Silva, Aravinda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787251/
https://www.ncbi.nlm.nih.gov/pubmed/31601808
http://dx.doi.org/10.1038/s41467-019-12677-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787251/
https://www.ncbi.nlm.nih.gov/pubmed/31601808
http://dx.doi.org/10.1038/s41467-019-12677-6

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