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Light-induced Nrf2(−/−) mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel
Elevated oxidative stress and associated reactive oxygen species (ROS) accumulation are hallmarks in the induction and progression of age-related macular degeneration (AMD). By exposing nuclear factor erythroid 2-related factor (Nrf2) knockout (Nrf2(−/−)) mice to mild white light, we were able to ge...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787253/ https://www.ncbi.nlm.nih.gov/pubmed/31601909 http://dx.doi.org/10.1038/s41598-019-51151-7 |