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Light-induced Nrf2(−/−) mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel

Elevated oxidative stress and associated reactive oxygen species (ROS) accumulation are hallmarks in the induction and progression of age-related macular degeneration (AMD). By exposing nuclear factor erythroid 2-related factor (Nrf2) knockout (Nrf2(−/−)) mice to mild white light, we were able to ge...

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Detalles Bibliográficos
Autores principales:	Wang, Kai, Zheng, Min, Lester, Kaitlyn Lee, Han, Zongchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787253/ https://www.ncbi.nlm.nih.gov/pubmed/31601909 http://dx.doi.org/10.1038/s41598-019-51151-7

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