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Altered metabolic gene expression in the brain of a triprolyl-human amylin transgenic mouse model of type 2 diabetes

Type 2 diabetes mellitus is a major health concern worldwide; however, the molecular mechanism underlying its development is poorly understood. The hormone amylin is postulated to be involved, as human amylin forms amyloid in the pancreases of diabetic patients, and oligomers have been shown to be c...

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Detalles Bibliográficos
Autores principales: Nie, Tina, Zhang, Shaoping, Vazhoor Amarsingh, Greeshma, Liu, Hong, McCann, Mark J., Cooper, Garth J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787337/
https://www.ncbi.nlm.nih.gov/pubmed/31601900
http://dx.doi.org/10.1038/s41598-019-51088-x