Truncated O‐glycans promote epithelial‐to‐mesenchymal transition and stemness properties of pancreatic cancer cells

Aberrant expression of Sialyl‐Tn (STn) antigen correlates with poor prognosis and reduced patient survival. We demonstrated that expression of Tn and STn in pancreatic ductal adenocarcinoma (PDAC) is due to hypermethylation of Core 1 synthase specific molecular chaperone (COSMC) and enhanced the mal...

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Detalles Bibliográficos
Autores principales: Thomas, Divya, Sagar, Satish, Caffrey, Thomas, Grandgenett, Paul M., Radhakrishnan, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787448/
https://www.ncbi.nlm.nih.gov/pubmed/31389667
http://dx.doi.org/10.1111/jcmm.14572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787448/
https://www.ncbi.nlm.nih.gov/pubmed/31389667
http://dx.doi.org/10.1111/jcmm.14572

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