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Anatomically specific reactive oxygen species production participates in Marfan syndrome aneurysm formation

Marfan syndrome (MFS) is a connective tissue disorder that results in aortic root aneurysm formation. Reactive oxygen species (ROS) seem to play a role in aortic wall remodelling in MFS, although the mechanism remains unknown. MFS Fbn1(C1039G/+) mouse root/ascending (AS) and descending (DES) aortic...

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Detalles Bibliográficos
Autores principales: Emrich, Fabian, Penov, Kiril, Arakawa, Mamoru, Dhablania, Nathan, Burdon, Grayson, Pedroza, Albert J., Koyano, Tiffany K., Kim, Young M., Raaz, Uwe, Connolly, Andrew J., Iosef, Cristiana, Fischbein, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787454/
https://www.ncbi.nlm.nih.gov/pubmed/31402541
http://dx.doi.org/10.1111/jcmm.14587