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Synergistic combination of DT‐13 and Topotecan inhibits aerobic glycolysis in human gastric carcinoma BGC‐823 cells via NM IIA/EGFR/HK II axis

DT‐13 combined with topotecan (TPT) showed stronger antitumour effects in mice subcutaneous xenograft model compared with their individual effects in our previous research. Here, we further observed the synergistically effect in mice orthotopic xenograft model. Metabolomics analysis showed DT‐13 com...

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Detalles Bibliográficos
Autores principales: Yu, Xiao‐Wen, Wei, Dandan, Gao, Ying‐Sheng, Du, Hong‐Zhi, Yu, Bo‐Yang, Li, Rui‐Ming, Qian, Chang‐Min, Luo, Xue‐Jun, Yuan, Sheng‐Tao, Wang, Jun‐Song, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787456/
https://www.ncbi.nlm.nih.gov/pubmed/31397978
http://dx.doi.org/10.1111/jcmm.14523