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Synergistic combination of DT‐13 and Topotecan inhibits aerobic glycolysis in human gastric carcinoma BGC‐823 cells via NM IIA/EGFR/HK II axis
DT‐13 combined with topotecan (TPT) showed stronger antitumour effects in mice subcutaneous xenograft model compared with their individual effects in our previous research. Here, we further observed the synergistically effect in mice orthotopic xenograft model. Metabolomics analysis showed DT‐13 com...
Autores principales: | Yu, Xiao‐Wen, Wei, Dandan, Gao, Ying‐Sheng, Du, Hong‐Zhi, Yu, Bo‐Yang, Li, Rui‐Ming, Qian, Chang‐Min, Luo, Xue‐Jun, Yuan, Sheng‐Tao, Wang, Jun‐Song, Sun, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787456/ https://www.ncbi.nlm.nih.gov/pubmed/31397978 http://dx.doi.org/10.1111/jcmm.14523 |
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