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Berberine attenuates XRCC1‐mediated base excision repair and sensitizes breast cancer cells to the chemotherapeutic drugs

Berberine (BBR) is a natural isoquinoline alkaloid, which is used in traditional medicine for its anti‐microbial, anti‐protozoal, anti‐diarrhoeal activities. Berberine interacts with DNA and displays anti‐cancer activities, yet its effects on cellular DNA repair and on synthetic treatments with chem...

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Detalles Bibliográficos
Autores principales: Gao, Xingjie, Wang, Jing, Li, Meiqi, Wang, Jia, Lv, Jian, Zhang, Lu, Sun, Caifeng, Ji, Jiamei, Yang, Wenbo, Zhao, Zinan, Mao, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787507/
https://www.ncbi.nlm.nih.gov/pubmed/31338966
http://dx.doi.org/10.1111/jcmm.14560